Product Information
Registration Status: ActiveALOSYN EYE DROPS is approved to be sold in Singapore with effective from 2008-01-24. It is marketed by PETER CHIA MARKETING PTE LTD, with the registration number of SIN13400P.
This product contains Antazoline 0.50MG/ML, and Tetrahydrozoline 0.40MG/ML in the form of SOLUTION, STERILE. It is approved for OPHTHALMIC use.
This product is manufactured by ASHFORD LABORATORIES LTD. in MACAU.
It is an Over-the-counter Medicine that can be freely obtained from any retailer
Description
Antazoline is a 1st generation antihistamine that also anticholinergic properties used to relieve nasal congestion and in eye drops, usually in combination with naphazoline, to relieve the symptoms of allergic conjunctivitis.
Indication
Used to relieve nasal congestion and in eye drops, usually in combination with naphazoline, to relieve the symptoms of allergic conjunctivitis.
Mechanism of Action
Antazoline binds to the histamine H1 receptor. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms brought on by histamine.
Active Ingredient/Synonyms
Antazoline | Antazoline |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.
Description
Tetryzoline (also known as Tetrahydrozoline), a derivative of imidazoline, is found in over-the-counter eye drops and nasal sprays. Other derivatives include naphazoline, oxymetazoline, and xylometazoline. Johnson and Johnson manufactures tetryzoline eye drops under the brand Visine ®.
Indication
For temporary relief of discomfort and redness of the eye due to minor eye irritations.
Mechanism of Action
Tetryzoline is an alpha-adrenergic agonist. Its primary action is the constriction of conjunctival blood vessels, which serves to decrease eye redness caused by minor ocular irritants.
Toxicity
Reports of prolonged cardiovascular effects after unintentional ingestion of tetrahydrozoline are noted in the literature.
Active Ingredient/Synonyms
(RS)-2-(1,2,3,4-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole | Tetrahydrozoline | Tetrizolina | Tetryzolin | Tétryzoline | Tetryzolinum | Tetryzoline |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.