Product Information
Registration Status: ActiveAPO-K TABLET 600mg is approved to be sold in Singapore with effective from 1991-08-19. It is marketed by PHARMAFORTE SINGAPORE PTE LTD, with the registration number of SIN06498P.
This product contains Potassium Chloride 600mg in the form of TABLET, FILM-COATED. It is approved for ORAL use.
This product is manufactured by APOTEX INC in CANADA.
It is an Over-the-counter Medicine that can be freely obtained from any retailer
Description
A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives.
Indication
For use as an electrolyte replenisher and in the treatment of hypokalemia.
Mechanism of Action
Supplemental potassium in the form of high potassium food or potassium chloride may be able to restore normal potassium levels.
Pharmacokinetics
- Absorption
- Potassium is a normal dietary constituent and under steady-state conditions the amount of potassium absorbed from the gastrointestinal tract is equal to the amount excreted in the urine.
- Distribution
- Metabolism
- Elimination
Toxicity
The administration of oral potassium salts to persons with normal excretory mechanisms for potassium rarely causes serious hyperkalemia. However, if excretory mechanisms are impaired, of if potassium is administered too rapidly intravenously, potentially fatal hyperkalemia can result. It is important to recognize that hyperkalemia is usually asymptomatic and may be manifested only by an increased serum potassium concentration (6.5-8.0 mEq/L) and characteristic electrocardiographic changes (peaking of T-waves, loss of P-wave, depression of S-T segment, and prolongation of the QT interval). Late manifestations include muscle paralysis and cardiovascular collapse from cardiac arrest (9-12 mEq/L).
Active Ingredient/Synonyms
[KCl] | Chlorid draselny | Chloride of potash | Kaliumchlorid | KCl | Monopotassium chloride | Muriate of potash | Sylvite | Potassium Chloride |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.