Product Information

Registration Status: Active

ARCALION TABLET 200mg is approved to be sold in Singapore with effective from 1991-03-05. It is marketed by SERVIER (S) PTE LTD, with the registration number of SIN06159P.

This product contains Sulbutiamine 200mg in the form of TABLET, SUGAR-COATED. It is approved for ORAL use.

This product is manufactured by LES LABORATOIRES SERVIER INDUSTRIE in FRANCE.

It is an Over-the-counter Medicine that can be freely obtained from any retailer



Sulbutiamine is a synthetic derivative of thiamine (vitamin B1) under the market name Arcalion that is composed of two modified thiamine molecules to form a dimer. Due to its highly lipophilic property, sulbutiamine crosses the blood-brain barrier more readily than thiamine and increases the levels of thiamine and thiamine phosphate esters in the brain. Although its clinical efficacy is not yet defined, sulbutiamine is used to treat asthenia. While its other uses include improvement of erectile dysfunction and reduction of psycho-behavioural inhibition, sulbutiamine showed evidence of modulatory effect on dopaminergic and glutamatergic cortical transmissions. The chronic administration of the drug has demonstrated to improve long term memory formation in mice.

Active Ingredient/Synonyms

Sulbutiamine | Sulbutiamine |

Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.


  1. Health Science Authority of Singapore - Reclassified POM
  2. Drugbank