Product Information
Registration Status: ActiveGASCOVID ADVANCE LIQUID is approved to be sold in Singapore with effective from 2020-11-17. It is marketed by GOLDPLUS UNIVERSAL PTE LTD, with the registration number of SIN16042P.
This product contains Potassium Bicarbonate 200MG/10ML, and Sodium Alginate 1000MG/10ML in the form of SUSPENSION. It is approved for ORAL use.
This product is manufactured by Hovid Bhd in MALAYSIA.
It is an Over-the-counter Medicine that can be freely obtained from any retailer
Description
Potassium bicarbonate is a white, crystalline, slightly alkaline and salty substance. It is produced by the passage of carbon dioxide through an aqueous potassium carbonate solution. It is used in medicine as an antacid.[T141] It is registered in the FDA under the section of suitable, safe and effective ingredients for OTC antacids.[L1836] This FDA denomination classifies potassium bicarbonate as a GRAS ingredient.[L1837]
Indication
Potassium bicarbonate is used as an antacid, electrolyte replenisher and potassium supplement. It can also be used as an excipient in drug formulations.[L1837] An antacid is a medication used to neutralize gastric acid in a short timeframe after ingestion and the effect is soon overcome by meal-stimulated acid secretion.[A32214]
Mechanism of Action
The antacid potential of potassium bicarbonate is attained by increasing the gastrointestinal pH by neutralizing hydrochloric acid.[T144] The increase in pH results in suppression of the action of pepsin which is the enzyme that exacerbates ulceration due to the presence of acid.[T143]
Pharmacokinetics
- Absorption
- Potassium bicarbonate intake is done mainly in the small intestine in which approximately 90% of the potassium will be absorbed by passive diffusion.[A32222]
- Distribution
- Metabolism
- Elimination
Toxicity
Potassium bicarbonate does not contain any toxic chemicals and it is not listed as a carcinogenic or a potential carcinogen.[L1837] Potassium bicarbonate is also considered safe in pregnancy as the current data do not suggest a teratogenic potential or any developmental toxicity.[T142]
Active Ingredient/Synonyms
Carbonic acid, monopotassium salt | Potassium hydrogen carbonate | Potassium bicarbonate |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.