Product Information
Registration Status: ActiveMAGNESIUM TRISILICATE COMPOUND TABLET BP is approved to be sold in Singapore with effective from 1991-01-10. It is marketed by SUNWARD PHARMACEUTICAL PTE LTD, with the registration number of SIN06599P.
This product contains Aluminium Hydroxide Dried 120mg, and Magnesium Trisilicate 250mg in the form of TABLET. It is approved for ORAL use.
This product is manufactured by SUNWARD PHARMACEUTICAL PTE LTD in SINGAPORE.
It is an Over-the-counter Medicine that can be freely obtained from any retailer
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.
Description
Magnesium trisilicate is an inorganic compound that is used as an antacid in the treatment of peptic ulcers.
Indication
For the treatment of peptic ulcers. Relieving indigestion and heartburn.
Mechanism of Action
The gelatinous silicon dioxide, formed by the reaction of magnesium trisilicate with gastric contents is said to protect ulcerated mucosal surfaces and favor healing.
Pharmacokinetics
- Absorption
- The hydrated silicon dioxide formed in the stomach and passes into the intestinal track where, silica can be partly absorbed.
- Distribution
- The hydrated silicon dioxide formed in the stomach and passes into the intestinal track.
- Metabolism
- Elimination
Clearance
Maximum magnesium clearance is directly proportional to creatinine clearance.
Toxicity
Adequate doses of magnesium trisilicate may cause diarrhea due to the action of soluble magnesium salts in the enteric tract. Approx 5% of the magnesium is absorbed.
Active Ingredient/Synonyms
Magnesium Trisilicate | Magnesium Trisilicate |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.