Product Information
Registration Status: ActiveOPTIZOLINE EYE DROPS 0.05% is approved to be sold in Singapore with effective from 1992-03-23. It is marketed by APEX PHARMA MARKETING PTE LTD, with the registration number of SIN06918P.
This product contains Tetrahydrozoline 0.05% in the form of SOLUTION. It is approved for OPHTHALMIC use.
This product is manufactured by XEPA-SOUL PATTINSON (MALAYSIA) SDN BHD in MALAYSIA.
It is an Over-the-counter Medicine that can be freely obtained from any retailer
Description
Tetryzoline (also known as Tetrahydrozoline), a derivative of imidazoline, is found in over-the-counter eye drops and nasal sprays. Other derivatives include naphazoline, oxymetazoline, and xylometazoline. Johnson and Johnson manufactures tetryzoline eye drops under the brand Visine ®.
Indication
For temporary relief of discomfort and redness of the eye due to minor eye irritations.
Mechanism of Action
Tetryzoline is an alpha-adrenergic agonist. Its primary action is the constriction of conjunctival blood vessels, which serves to decrease eye redness caused by minor ocular irritants.
Toxicity
Reports of prolonged cardiovascular effects after unintentional ingestion of tetrahydrozoline are noted in the literature.
Active Ingredient/Synonyms
(RS)-2-(1,2,3,4-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole | Tetrahydrozoline | Tetrizolina | Tetryzolin | Tétryzoline | Tetryzolinum | Tetryzoline |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.