Product Information
Registration Status: ActiveOTRIVIN NASAL SPRAY 0.1% is approved to be sold in Singapore with effective from 2001-08-14. It is marketed by GSK CONSUMER HEALTHCARE SINGAPORE PTE LTD, with the registration number of SIN11624P.
This product contains Xylometazoline 1mg/ml in the form of SPRAY. It is approved for NASAL use.
This product is manufactured by NOVARTIS CONSUMER HEALTH SA in SWITZERLAND.
It is an Over-the-counter Medicine that can be freely obtained from any retailer
Description
A nasal vasoconstricting decongestant drug which acts by binding to the same receptors as adrenaline. It is applied as a spray or as drops into the nose to ease inflammation and congestion of the nasal passageways. It binds alpha-adrenergic receptors to activate the adrenal system which causes systemic vasoconstriction, thereby easing nasal congestion.
Indication
It is used for treating nasal congestion and minor inflammation due to allergies or colds.
Mechanism of Action
Xylometazoline is a direct acting sympathomimetic drug, which acts on alpha-adrenergic receptors in the arterioles of the nasal mucosa. This activates the adrenal system to yield systemic vasoconstrction. In producing vasoconstriction, the result is a decrease in blood flow in the nasal passages and consequently decreased nasal congestion.
Active Ingredient/Synonyms
Balminil | Xylomethazoline | Xylometazoline |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.