Product Information
Registration Status: ActiveOXY-NASE NASAL DROPS 0.05% is approved to be sold in Singapore with effective from 1998-09-01. It is marketed by ZUELLIG PHARMA PTE LTD, with the registration number of SIN09606P.
This product contains Oxymetazoline 0.05% w/v in the form of SOLUTION. It is approved for NASAL use.
This product is manufactured by HOE PHARMACEUTICALS SDN BHD in MALAYSIA.
It is an Over-the-counter Medicine that can be freely obtained from any retailer
Description
A direct acting sympathomimetic used as a vasoconstrictor to relieve nasal congestion. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1251)
Indication
For treatment of nasal congestion and redness associated with minor irritations of the eye
Mechanism of Action
Oxymetazoline is a direct acting sympathomimetic amine, which acts on alpha-adrenergic receptors in the arterioles of the conjunctiva and nasal mucosa. It produces vasoconstriction, resulting in decreased conjunctival congestion in ophthalmic. In nasal it produces constriction, resulting in decreased blood flow and decreased nasal congestion.
Active Ingredient/Synonyms
2-(4-Tert-butyl-2,6-dimethyl-3-hydroxybenzyl)-2-imidazoline | 3-[(4,5-dihydro-1H-Imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethylphenol | 6-t-Butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol | 6-Tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol | Oximetazolinum | Oxymetazolina | Oxymetazolinum | Oxymethazoline | Oxymetozoline | Oxymetazoline |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.