Product Information
Registration Status: ActiveSWIFF MIXTURE is approved to be sold in Singapore with effective from 1999-08-07. It is marketed by POLYMEDIC TRADING ENTERPRISE PTE LTD, with the registration number of SIN11016P.
This product contains Dibasic 0.9g/5ml, and Monobasic 2.4g/5ml in the form of SOLUTION. It is approved for ORAL use.
This product is manufactured by BERLIN PHARMACEUTICAL INDUSTRY CO LTD in THAILAND.
It is an Over-the-counter Medicine that can be freely obtained from any retailer
Description
Aluminium monostearate is an organic compound which is a salt of stearic acid and aluminium. It has the molecular formula Al(OH)2C18H35O2. It is also referred to as dihydroxyaluminium or dihydroxy(stearato)aluminium. It is used to form gels in the packaging of pharmaceuticals, and in the preparation of colors for cosmetics. It is usually safe in commercial products, but aluminium may accumulate in the body.
Mechanism of Action
Antacids perform a neutralization reaction, ie. they buffer gastric acid, raising the pH to reduce acidity in the stomach. When gastric hydrochloric acid reaches the nerves in the gasitrointestinal mucosa, they signal pain to the central nervous system. This happens when these nerves are exposed, as in peptic ulcers. The gastric acid may also reach ulcers in the esophagus or the duodenum. Other mechanisms may contribute, such as the effect of aluminum ions inhibiting smooth muscle cell contraction and delaying gastric emptying. Aluminum is known to bind troponin C (a muscle protein) and to interfere with voltage-dependent calcium transport. Aluminum also binds to and inhibits the activity of mitochondrial voltage gated channels (VDAC).
Active Ingredient/Synonyms
Aluminium, dihydroxide stearate | Aluminum monostearate | Aluminum stearate 300 | Dibasic aluminium stearate | Dibasic aluminum stearate | Dihydroxy(stearato)aluminium | Dihydroxy(stearato)aluminum | Dihydroxyaluminum stearate | Aluminium monostearate |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.