Product Information
Registration Status: ActiveSIN10526P
BOMEX TABLET 4mg is approved to be sold in Singapore with effective from 1998-08-12. It is marketed by YUNG SHIN PHARMACEUTICAL (SINGAPORE) PTE LTD, with the registration number of SIN10526P.
This product contains Brompheniramine 4mg in the form of TABLET. It is approved for ORAL use.
This product is manufactured by Y S P INDUSTRIES (M) SDN BHD in MALAYSIA.
It is a Pharmacy Only Medicine that can be obtained from a pharmacist at a retail pharmacy.
Product Reference
Important Note: For generic product, the SPC/PIL provided may not be brand specific.
{{/items}} {{^items}}Description
Histamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria. [PubChem]
Indication
For the treatment of the symptoms of the common cold and allergic rhinitis, such as runny nose, itchy eyes, watery eyes, and sneezing.
Mechanism of Action
Brompheniramine works by acting as an antagonist of the H1 histamine receptors. It also functions as a moderately effective anticholingeric agent, likely an antimuscarinic agent similar to other common antihistamines such as diphenhydramine. Its effects on the cholinergic system may include side-effects such as drowsiness, sedation, dry mouth, dry throat, blurred vision, and increased heart rate.
Pharmacokinetics
- Absorption
- Antihistamines are well absorbed from the gastrointestinal tract after oral administration.
- Distribution
- Metabolism
- Hepatic (cytochrome P-450 system), some renal.
- Elimination
Toxicity
Oral, rat: LD50 = 318 mg/kg. Signs of overdose include fast or irregular heartbeat, mental or mood changes, tightness in the chest, and unusual tiredness or weakness.
Active Ingredient/Synonyms
[3-(4-Bromo-phenyl)-3-pyridin-2-yl-propyl]-dimethyl-amine | 1-(P-Bromophenyl)-1-(2-pyridyl)-3-dimethylaminopropane | 2-(P-Bromo-alpha-(2-dimethylaminoethyl)benzyl)pyridine | 3-(4-Bromophenyl)-N,N-dimethyl-3-(2-pyridinyl)-1-propanamine | 3-(P-Bromophenyl)-3-(2-pyridyl)-N,N-dimethylpropylamine | BPN | Bromfeniramina | Brompheniramin | Bromphéniramine | Brompheniraminum | Brompheniramine |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.