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METEOSPASMYL CAPSULE

Product Information

Registration Status: Active

SIN08890P

METEOSPASMYL CAPSULE is approved to be sold in Singapore with effective from 1996-04-09. It is marketed by POLYMEDIC TRADING ENTERPRISE PTE LTD, with the registration number of SIN08890P.

This product contains Alverine Citrate 60mg, and Simethicone 300mg in the form of CAPSULE, LIQUID FILLED. It is approved for ORAL use.

This product is manufactured by LABORATOIRES MAYOLY SPINDLER in FRANCE.

It is a Pharmacy Only Medicine that can be obtained from a pharmacist at a retail pharmacy.

Product Reference
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Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.


Description

Simethicone is an orally administered antifoaming agent. It is mainly used to reduce gas from the gastrointestinal tract (GIT) in patients complaining from recurrent flatulence. Simethicone is a mixture of polydimethylsiloxane and hydrated silica gel. It exerts its action locally in the GIT, it is not absorbed into the blood stream. The main side effects of simethicone are GIT related including: mild diarrhea, nausea and vomiting.

Indication

1. To relieve pain and discomfort caused by excess gas in the intestine and stomach in cases such as flatulence and post operative gaseous distention. 2. It could be used also prior to an endoscopy to eliminate foam, gas and air from the gastrointestinal tract to reduce gas shadow which will result in better visualization.

Mechanism of Action

Decreases the surface tension of gas bubbles thereby disperses and prevents gas pockets in the GI system.

Pharmacokinetics

Absorption
Not absorbed following oral administration.
Distribution
Simethicone is pharmacologically inert and is not absorbed from the gastrointestinal tract.
Metabolism
The drug is not absorbed and it is excreted in the feces unchanged.
Elimination

Clearance

Excreted unchanged in feces.

Toxicity

LD50 (oral, rat): 4070 mg/Kg.

Active Ingredient/Synonyms

Simeticone | Simethicone |


Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.

References

  1. Health Science Authority of Singapore - Reclassified POM
  2. Drugbank

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