Product Information
Registration Status: ActiveSIN03114P
SCOPODERM TTS 1.5 TRANSDERMAL THERAPEUTIC SYSTEM is approved to be sold in Singapore with effective from 1989-09-06. It is marketed by GSK CONSUMER HEALTHCARE SINGAPORE PTE LTD, with the registration number of SIN03114P.
This product contains Scopolamine 1.5mg/2.5 sq cm in the form of PATCH. It is approved for TRANSDERMAL use.
This product is manufactured by ALZA CORPORATION in UNITED STATES.
It is a Pharmacy Only Medicine that can be obtained from a pharmacist at a retail pharmacy.
Product Reference
Important Note: For generic product, the SPC/PIL provided may not be brand specific.
{{/items}} {{^items}}Description
A muscarinic antagonist used to study binding characteristics of muscarinic cholinergic receptors. [PubChem]
Indication
Used as adjunctive therapy for the treatment of peptic ulcer. Also used to treat nausea and vomiting due to motion sickness.
Mechanism of Action
Methscopolamine acts by interfering with the transmission of nerve impulses by acetylcholine in the parasympathetic nervous system (specifically the vomiting center). It does so by acting as a muscarinic antagonist.
Pharmacokinetics
- Absorption
- Poorly and unreliably absorbed, total absorption is 10-25%.
- Distribution
- Metabolism
- Little is known about the fate and excretion of methscopolamine.
- Elimination
Toxicity
Symptoms of a methscopolamine overdose include headache, nausea, vomiting, dry mouth, difficulty swallowing, blurred vision, dilated pupils, hot, dry skin, dizziness; drowsiness, confusion, anxiety, seizures, weak pulse, and an irregular heartbeat. In addition, a curare-like action may occur, i.e., neuromuscular blockade leading to muscular weakness and possible paralysis.
Active Ingredient/Synonyms
(−)-scopolamine methobromide | (−)-scopolamine methyl bromide | Hyoscine Methobromide | Hyoscine methyl bromide | Methscopolamine bromide | N-methylhyoscine bromide | N-methylscopolammonium bromide | Scopolamine Methobromide | Scopolamine methyl bromide | Methylscopolamine bromide |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.