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ADDAMEL N FOR INFUSION

Product Information

Registration Status: Active

SIN06807P

ADDAMEL N FOR INFUSION is approved to be sold in Singapore with effective from 1992-01-31. It is marketed by FRESENIUS KABI (SINGAPORE) PTE LTD, with the registration number of SIN06807P.

This product contains Chromic Chloride.6H2O 5.33mcg/ml,Copper Chloride.2H2O 0.34mg/ml,Ferric Chloride.6H2O 0.54mg/ml,Manganese Chloride.4H2O 99mcg/ml,Potassium Iodide 16.6mcg/ml,Sodium Fluoride 0.21mg/ml,Sodium Molybdate.2H2O 4.85mcg/ml,Sodium Selenite 6.9mcg/ml, and Zinc Chloride 1.36mg/ml in the form of INJECTION. It is approved for INTRAVENOUS use.

This product is manufactured by FRESENIUS KABI NORGE AS in NORWAY.

It is a Prescription Only Medicine that can only be obtained from a doctor or a dentist, or a pharmacist with a prescription from a Singapore-registered doctor or dentist.

Product Reference
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Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.



Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.



Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.



Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.


Description

Saturated solution of Potassium Iodide (SSKI) is used pharmaceutically for emergency use in patients experiencing acute symptoms of severe hyperglycemia (also known as thyroid storm or thyrotoxic crisis). SSKI can also be used for radioiodine-contamination emergencies or in preparation of thyrotoxic patients for thyroidectomy.

Indication

Potassium Iodide is oral antithyroid agent. Potassium Iodide is used as an adjunct to other antithyroid agents in the treatment of hyperthyroidism and thyrotoxicosis and preoperatively to induce thyroid involution.

Active Ingredient/Synonyms

Kaliumiodid | KI | Potassium iodide | Potassium Iodide |


Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.


Description

Sodium fluoride is an inorganic chemical compound. A colorless solid, it is a source of the fluoride ion in diverse applications. Sodium fluoride is less expensive and less hygroscopic than the related salt potassium fluoride.

Indication

To prevent cavities.

Mechanism of Action

Fluorides interfere with electron transport and calcium metabolism. Calcium is essential for maintaining cardiac membrane potentials and in regulating coagulation.

Pharmacokinetics

Absorption
Absorbed readily and almost completely from the GI tract. A large amount of an oral dose may be absorbed in the stomach; rate of absorption may depend on the gastric pH.
Distribution
Stored in bones and developing teeth after absorption. Fluoride is distributed into sweat, tears, hair, and saliva. Fluoride crosses the placental barrier and is distributed into breast milk.
Metabolism
Not metabolized.
Elimination

Toxicity

Symptom onset usually occurs within minutes of exposure, but may be delayed. Manifestations of fluoride toxicity are predominantly gastrointestinal (GI), but neurologic and cardiovascular effects also occur.

Active Ingredient/Synonyms

Sodium fluoride | Sodium fluoride |


Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.



Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.



Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.



Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.

References

  1. Health Science Authority of Singapore - Reclassified POM
  2. Drugbank

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