Product Information
Registration Status: ActiveADDAVEN CONCENTRATE FOR SOLUTION FOR INFUSION is approved to be sold in Singapore with effective from 2017-07-24. It is marketed by FRESENIUS KABI (SINGAPORE) PTE LTD, with the registration number of SIN15302P.
This product contains Copper Chloride Dihydrate 102.3mcg/ml,Ferric Chloride Hexahydrate 540mcg/ml,Manganese Chloride Tetrahydrate 19.79mcg/ml,Potassium Iodide 16.6mcg/ml,Sodium Fluoride 210mcg/ml,Sodium Molybdate Dihydrate 4.85mcg/ml,Sodium Selenite Anhydrous 17.29mcg/ml, and Zinc Chloride 1050mcg/ml in the form of INFUSION, SOLUTION CONCENTRATE. It is approved for INTRAVENOUS use.
This product is manufactured by Fresenius Kabi Norge AS in NORWAY.
It is a Prescription Only Medicine that can only be obtained from a doctor or a dentist, or a pharmacist with a prescription from a Singapore-registered doctor or dentist.
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.
Description
Saturated solution of Potassium Iodide (SSKI) is used pharmaceutically for emergency use in patients experiencing acute symptoms of severe hyperglycemia (also known as thyroid storm or thyrotoxic crisis). SSKI can also be used for radioiodine-contamination emergencies or in preparation of thyrotoxic patients for thyroidectomy.
Indication
Potassium Iodide is oral antithyroid agent. Potassium Iodide is used as an adjunct to other antithyroid agents in the treatment of hyperthyroidism and thyrotoxicosis and preoperatively to induce thyroid involution.
Active Ingredient/Synonyms
Kaliumiodid | KI | Potassium iodide | Potassium Iodide |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.
Description
Sodium fluoride is an inorganic chemical compound. A colorless solid, it is a source of the fluoride ion in diverse applications. Sodium fluoride is less expensive and less hygroscopic than the related salt potassium fluoride.
Indication
To prevent cavities.
Mechanism of Action
Fluorides interfere with electron transport and calcium metabolism. Calcium is essential for maintaining cardiac membrane potentials and in regulating coagulation.
Pharmacokinetics
- Absorption
- Absorbed readily and almost completely from the GI tract. A large amount of an oral dose may be absorbed in the stomach; rate of absorption may depend on the gastric pH.
- Distribution
- Stored in bones and developing teeth after absorption. Fluoride is distributed into sweat, tears, hair, and saliva. Fluoride crosses the placental barrier and is distributed into breast milk.
- Metabolism
- Not metabolized.
- Elimination
Toxicity
Symptom onset usually occurs within minutes of exposure, but may be delayed. Manifestations of fluoride toxicity are predominantly gastrointestinal (GI), but neurologic and cardiovascular effects also occur.
Active Ingredient/Synonyms
Sodium fluoride | Sodium fluoride |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.