Product Information
Registration Status: ActiveANALCAM TABLET 20mg is approved to be sold in Singapore with effective from 1997-05-12. It is marketed by DUOPHARMA (SINGAPORE) PTE LTD, with the registration number of SIN09570P.
This product contains Tenoxicam 20mg in the form of TABLET. It is approved for ORAL use.
This product is manufactured by DUOPHARMA (M) SDN BHD in MALAYSIA.
It is a Prescription Only Medicine that can only be obtained from a doctor or a dentist, or a pharmacist with a prescription from a Singapore-registered doctor or dentist.
Description
Tenoxicam, an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain.
Indication
For the treatment of rheumatoid arthritis, osteoarthritis, backache, and pain.
Mechanism of Action
The antiinflammatory effects of tenoxicam may result from the inhibition of the enzyme cycooxygenase and the subsequent peripheral inhibition of prostaglandin synthesis. As prostaglandins sensitize pain receptors, their inhibition accounts for the peripheral analgesic effects of tenoxicam. Antipyresis may occur by central action on the hypothalamus, resulting in peripheral dilation, increased cutaneous blood flow, and subsequent heat loss.
Pharmacokinetics
- Absorption
- Oral absorption of tenoxicam is rapid and complete (absolute bioavailability 100%).
- Distribution
- Metabolism
- Tenoxicam is metabolized in the liver to several pharmacologically inactive metabolites (mainly 5'-hydroxy-tenoxicam).
- Elimination
Active Ingredient/Synonyms
Tenoxicam | Ténoxicam | Tenoxicamum | Tenoxicam |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.