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CEFTAZIDIME ALVOGEN POWDER FOR SOLUTION FOR INJECTION AND INFUSION 1G/ VIAL

Product Information

Registration Status: Active

SIN14738P

CEFTAZIDIME ALVOGEN POWDER FOR SOLUTION FOR INJECTION AND INFUSION 1G/ VIAL is approved to be sold in Singapore with effective from 2015-02-27. It is marketed by ALVOGEN SINGAPORE PTE LTD, with the registration number of SIN14738P.

This product contains Ceftazidime 1.0g/ vial in the form of INJECTION, POWDER, FOR SOLUTION. It is approved for INTRAVENOUS, INTRAMUSCULAR use.

This product is manufactured by SHENZHEN ZHIJUN PHARMACEUTICAL CO. in CHINA.

It is a Prescription Only Medicine that can only be obtained from a doctor or a dentist, or a pharmacist with a prescription from a Singapore-registered doctor or dentist.

Product Reference
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Description

Semisynthetic, broad-spectrum antibacterial derived from cephaloridine and used especially for Pseudomonas and other gram-negative infections in debilitated patients.

Indication

For the treatment of patients with infections caused by susceptible strains of organisms in the following diseases: lower respiratory tract infections,skin and skin structure infections, urinary tract infections, bacterial septicemia, bone and joint infections, gynecologic infections, intra abdominal infections (including peritonitis), and central nervous system infections (including meningitis).

Mechanism of Action

The bactericidal activity of ceftazidime results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins (PBPs).

Pharmacokinetics

Absorption
The absorption of ceftazidime is directly proportional to the size of the dose.
Distribution
Metabolism
Elimination

Clearance

* 115 mL/min

Toxicity

Ceftazidime overdosage has occurred in patients with renal failure. Reactions have included seizure activity, encephalopathy, asterixis, neuromuscular excitability, and coma.

Active Ingredient/Synonyms

CAZ | Ceftazidim | Ceftazidima | Ceftazidime | Ceftazidime anhydrous | Ceftazidimum | Ceftazidime |


Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.

References

  1. Health Science Authority of Singapore - Reclassified POM
  2. Drugbank

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