Product Information
Registration Status: ActiveSIN15325P
DATSCAN SOLUTION FOR INJECTION 74 MBQ/ML is approved to be sold in Singapore with effective from 2017-09-04. It is marketed by GE HEALTHCARE PTE LTD, with the registration number of SIN15325P.
This product contains Ioflupane (123I) 74 MBq/mL at reference time in the form of INJECTION, SOLUTION. It is approved for INTRAVENOUS use.
This product is manufactured by GE Healthcare B.V. in NETHERLANDS.
It is a Prescription Only Medicine that can only be obtained from a doctor or a dentist, or a pharmacist with a prescription from a Singapore-registered doctor or dentist.
Product Reference
Important Note: For generic product, the SPC/PIL provided may not be brand specific.
{{/items}} {{^items}}Description
Ioflupane (I-123) is a radiopharmaceutical used to image dopamine neurons and diagnose Parkinsonian syndromes.
Indication
Ioflupane I-123 is a SPECT (single photon emission computerized tomography) agent used to distinguish between Parkinson’s syndrome tremors and essential tremor.
Mechanism of Action
Iodine-123 labeled ioflupane binds to presynaptic dopamine transporters. When Iodine-123 decays, a gammay ray is emmitted and detected through SPECT.
Pharmacokinetics
- Absorption
- Absorption is 100% because administered I.V.
- Distribution
- Compared to the entire brain, about 30% of radioactivity is taken up by the striatum.
- Metabolism
- Elimination
Active Ingredient/Synonyms
123I-FP-CIT | 123I-Ioflupane | iodine ioflupane (123I) | ioflupane ((123)I) | ioflupane (123I) | Ioflupane I 123 | ioflupane I(123) | ioflupano (123I) | ioflupanum (123I) | Ioflupane I-123 |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.