Product Information
Registration Status: ActiveSIN08796P
DERMANOL-C CREAM 0.05% is approved to be sold in Singapore with effective from 1996-03-07. It is marketed by ICM PHARMA PTE LTD, with the registration number of SIN08796P.
This product contains Betamethasone Valerate 0.05% w/w, and Clioquinol 3% w/w in the form of CREAM. It is approved for TOPICAL use.
This product is manufactured by ICM PHARMA PTE LTD in SINGAPORE.
It is a Prescription Only Medicine that can only be obtained from a doctor or a dentist, or a pharmacist with a prescription from a Singapore-registered doctor or dentist.
Product Reference
Important Note: For generic product, the SPC/PIL provided may not be brand specific.
{{/items}} {{^items}}Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.
Description
Clioquinol was withdrawn in 1983 due to neurotoxicity.
Indication
Used as a topical antifungal treatment.
Mechanism of Action
Clioquinol is bacteriostatic, however, the precise mechanism of its action is unknown.
Pharmacokinetics
- Absorption
- Topical absorption is rapid and extensive, especially when the skin is covered with an occlusive dressing or if the medication is applied to extensive or eroded areas of the skin. Clioquinol is absorbed through the skin in sufficient amounts to affect thyroid function tests.
- Distribution
- Metabolism
- Elimination
Active Ingredient/Synonyms
5-Chlor-7-jod-8-hydroxy-chinolin | 5-Chloro-7-iodo-8-hydroxyquinoline | 5-Chloro-7-iodo-8-quinolinol | 5-chloro-7-iodoquinolin-8-ol | 5-Chloro-8-hydroxy-7-iodoquinoline | 7-Iodo-5-chloro-8-hydroxyquinoline | 7-Iodo-5-chloroxine | Chloroiodoquin | Clioquinolum | Iodochlorhydroxyquin | Iodochlorhydroxyquinoline | Iodochlorohydroxyquin | Iodochloroxyquinoline | Clioquinol |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.