Product Information
Registration Status: ActiveSIN11857P
DETRUSITOL SR CAPSULE 4mg is approved to be sold in Singapore with effective from 2002-01-04. It is marketed by PFIZER PTE LTD, with the registration number of SIN11857P.
This product contains Tolterodine 4mg in the form of CAPSULE. It is approved for ORAL use.
This product is manufactured by Catalent Pharma Solutions in UNITED STATES.
It is a Prescription Only Medicine that can only be obtained from a doctor or a dentist, or a pharmacist with a prescription from a Singapore-registered doctor or dentist.
Product Reference
Important Note: For generic product, the SPC/PIL provided may not be brand specific.
{{/items}} {{^items}}Description
Tolterodine is an antimuscarinic drug that is used to treat urinary incontinence. Tolterodine acts on M2 and M3 subtypes of muscarinic receptors.
Indication
For the treatment of overactive bladder (with symptoms of urinary frequency, urgency, or urge incontinence).
Mechanism of Action
Both tolterodine and its active metabolite, 5-hydroxymethyltolterodine, act as competitive antagonists at muscarinic receptors. This antagonism results in inhibition of bladder contraction, decrease in detrusor pressure, and an incomplete emptying of the bladder.
Active Ingredient/Synonyms
(+)-(R)-2-(alpha-(2-(Diisopropylamino)ethyl)benzyl)-p-cresol | (+)-Tolterodine | Tolterodina | Tolterodine | Tolterodinum | Tolterodine |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.