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DETRUSITOL TABLET 1mg

Product Information

Registration Status: Active

SIN09911P

DETRUSITOL TABLET 1mg is approved to be sold in Singapore with effective from 1998-07-28. It is marketed by PFIZER PTE LTD, with the registration number of SIN09911P.

This product contains Tolterodine 1mg in the form of TABLET, FILM-COATED. It is approved for ORAL use.

This product is manufactured by Pfizer Italia S.r.l. in ITALY.

It is a Prescription Only Medicine that can only be obtained from a doctor or a dentist, or a pharmacist with a prescription from a Singapore-registered doctor or dentist.

Product Reference
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Description

Tolterodine is an antimuscarinic drug that is used to treat urinary incontinence. Tolterodine acts on M2 and M3 subtypes of muscarinic receptors.

Indication

For the treatment of overactive bladder (with symptoms of urinary frequency, urgency, or urge incontinence).

Mechanism of Action

Both tolterodine and its active metabolite, 5-hydroxymethyltolterodine, act as competitive antagonists at muscarinic receptors. This antagonism results in inhibition of bladder contraction, decrease in detrusor pressure, and an incomplete emptying of the bladder.

Active Ingredient/Synonyms

(+)-(R)-2-(alpha-(2-(Diisopropylamino)ethyl)benzyl)-p-cresol | (+)-Tolterodine | Tolterodina | Tolterodine | Tolterodinum | Tolterodine |


Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.

References

  1. Health Science Authority of Singapore - Reclassified POM
  2. Drugbank

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