Product Information

Registration Status: Active

DOBUJECT INFUSION CONCENTRATE 50mg/ML is approved to be sold in Singapore with effective from 1988-11-05. It is marketed by M.B.D. MARKETING (S) PTE LTD, with the registration number of SIN01035P.

This product contains Dobutamine 50mg in the form of INJECTION. It is approved for INTRAVENOUS use.

This product is manufactured by SANTEN OY in SPAIN, andBerliMed S.A. in FINLAND.

It is a Prescription Only Medicine that can only be obtained from a doctor or a dentist, or a pharmacist with a prescription from a Singapore-registered doctor or dentist.



A beta-1 agonist catecholamine that has cardiac stimulant action without evoking vasoconstriction or tachycardia. It is proposed as a cardiotonic after myocardial infarction or open heart surgery.


For inotropic support in the short- term treatment of patients with cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures

Mechanism of Action

Dobutamine directly stimulates beta-1 receptors of the heart to increase myocardial contractility and stroke volume, resulting in increased cardiac output.

Active Ingredient/Synonyms

(+-)-4-(2-((3-(P-Hydroxyphenyl)-1-methylpropyl)amino)ethyl)pyrocatechol | 3,4-Dihydroxy-N-[3-(4-hydroxyphenyl)-1-methylpropyl]-beta-phenylethylamine | 4-{2-[3-(4-hydroxy-phenyl)-1-methyl-propylamino]-ethyl}-benzene-1,2-diol | DL-Dobutamine | Dobutamin | Dobutamina | Dobutamine | Dobutaminum | rac-Dobutamine | Racemic-dobutamine | Dobutamine |

Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.


  1. Health Science Authority of Singapore - Reclassified POM
  2. Drugbank