Product Information
Registration Status: ActiveDOBUTAMINE INJECTION 12.5mg/ML is approved to be sold in Singapore with effective from 1996-05-02. It is marketed by HOSPIRA SINGAPORE PTE LTD, with the registration number of SIN08702P.
This product contains Dobutamine 12.5mg/ml in the form of INJECTION. It is approved for INTRAVENOUS use.
This product is manufactured by HOSPIRA INC in UNITED STATES.
It is a Prescription Only Medicine that can only be obtained from a doctor or a dentist, or a pharmacist with a prescription from a Singapore-registered doctor or dentist.
Description
A beta-1 agonist catecholamine that has cardiac stimulant action without evoking vasoconstriction or tachycardia. It is proposed as a cardiotonic after myocardial infarction or open heart surgery.
Indication
For inotropic support in the short- term treatment of patients with cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures
Mechanism of Action
Dobutamine directly stimulates beta-1 receptors of the heart to increase myocardial contractility and stroke volume, resulting in increased cardiac output.
Active Ingredient/Synonyms
(+-)-4-(2-((3-(P-Hydroxyphenyl)-1-methylpropyl)amino)ethyl)pyrocatechol | 3,4-Dihydroxy-N-[3-(4-hydroxyphenyl)-1-methylpropyl]-beta-phenylethylamine | 4-{2-[3-(4-hydroxy-phenyl)-1-methyl-propylamino]-ethyl}-benzene-1,2-diol | DL-Dobutamine | Dobutamin | Dobutamina | Dobutamine | Dobutaminum | rac-Dobutamine | Racemic-dobutamine | Dobutamine |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.