Product Information

Registration Status: Active

DURATOCIN INJECTION 100mcg/ML is approved to be sold in Singapore with effective from 2003-08-25. It is marketed by FERRING PHARMACEUTICALS PTE LTD, with the registration number of SIN12401P.

This product contains Carbetocin 100mcg in the form of INJECTION. It is approved for INTRAVENOUS use.

This product is manufactured by Ferring GmbH in GERMANY.

It is a Prescription Only Medicine that can only be obtained from a doctor or a dentist, or a pharmacist with a prescription from a Singapore-registered doctor or dentist.



Carbetocin is a drug used to control postpartum hemorrhage, bleeding after giving birth. It is an analogue of oxytocin, and its action is similar to that of oxytocin -- it causes contraction of the uterus.


Used to control postpartum hemorrhage and bleeding after giving birth.

Mechanism of Action

Carbetocin binds to oxytocin receptors present on the smooth musculature of the uterus, resulting in rhythmic contractions of the uterus, increased frequency of existing contractions, and increased uterine tone. The oxytocin receptor content of the uterus is very low in the non-pregnant state, and increases during pregnancy, reaching a peak at the time of delivery.


Bioavailability is 80% following intramuscular injection.

Active Ingredient/Synonyms

1-Butanoic acid-2-(O-methyl-L-tyrosine)-1-carbaoxytocin | 1-Butyric acid-2-(3-(P-methoxyphenyl)-L-alanine)oxytocin | Carbetocino | Carbetocinum | Deamino-2-O-methyltyrosine-1-carbaoxytocin | Carbetocin |

Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.


  1. Health Science Authority of Singapore - Reclassified POM
  2. Drugbank