Product Information
Registration Status: ActiveSIN08849P
ETOMIDATE-LIPURO INJECTION 20mg/10ml is approved to be sold in Singapore with effective from 1996-08-14. It is marketed by B. BRAUN SINGAPORE PTE LTD, with the registration number of SIN08849P.
This product contains Etomidate 20mg/10ml in the form of INJECTION. It is approved for INTRAVENOUS use.
This product is manufactured by B BRAUN MELSUNGEN AG in GERMANY.
It is a Prescription Only Medicine that can only be obtained from a doctor or a dentist, or a pharmacist with a prescription from a Singapore-registered doctor or dentist.
Product Reference
Important Note: For generic product, the SPC/PIL provided may not be brand specific.
{{/items}} {{^items}}Description
Imidazole derivative anesthetic and hypnotic with little effect on blood gases, ventilation, or the cardiovascular system. It has been proposed as an induction anesthetic. [PubChem]
Indication
Used in the induction of general anesthesia.
Mechanism of Action
Etomidate binds at a distinct binding site associated with a Cl- ionopore at the GABAA receptor, increasing the duration of time for which the Cl- ionopore is open. The post-synaptic inhibitory effect of GABA in the thalamus is, therefore, prolonged.
Toxicity
Undesirable side effects of etomidate that may limit its use include pain on injection, myoclonus and adrenocortical suppression lasting 4-6 hours following an induction dose.
Active Ingredient/Synonyms
(+)-Ethyl 1-(alpha-methylbenzyl)imidazole-5-carboxylate | (+)-ethyl 1-(α-methylbenzyl)imidazole-5-carboxylate | (+)-etomidate | (R)-(+)-1-(alpha-Methylbenzyl)imidazole-5-carboxylic acid ethyl ester | (R)-1-(1-phenylethyl)-1H-imidazole-5-carboxylic acid ethyl ester | 3-((R)-1-Phenyl-ethyl)-3H-imidazole-4-carboxylic acid ethyl ester | Etomidate | Etomidato | Etomidatum | R-(+)-Ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate | Etomidate |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.