Product Information
Registration Status: ActiveHANACEF CAPSULE 500mg is approved to be sold in Singapore with effective from 1996-06-08. It is marketed by ZIWELL MEDICAL (S) PTE LTD, with the registration number of SIN08836P.
This product contains Cefadroxil 500mg in the form of CAPSULE. It is approved for ORAL use.
This product is manufactured by KOREAN DRUG CO LTD in KOREA, and in REPUBLIC OF.
It is a Prescription Only Medicine that can only be obtained from a doctor or a dentist, or a pharmacist with a prescription from a Singapore-registered doctor or dentist.
Description
Long-acting, broad-spectrum, water-soluble, cephalexin derivative.
Indication
For the treatment of the following infections (skin, UTI, ENT) caused by; S. pneumoniae, H. influenzae, staphylococci, S. pyogenes (group A beta-hemolytic streptococci), E. coli, P. mirabilis, Klebsiella sp, coagulase-negative staphylococci and Streptococcus pyogenes
Mechanism of Action
Like all beta-lactam antibiotics, cefadroxil binds to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, causing the inhibition of the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that cefadroxil interferes with an autolysin inhibitor.
Pharmacokinetics
- Absorption
- Cefadroxil is well absorbed on oral administration; food does not interfere with its absorption.
- Distribution
- Metabolism
- Elimination
Toxicity
Nausea, vomiting, diarrhoea, allergic rashes may occur
Active Ingredient/Synonyms
CDX | Cefadroxil anhydrous | Cefadroxilo | Cefadroxilum | Cephadroxil | D-Cefadroxil | Cefadroxil |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.