Product Information
Registration Status: ActiveIMPLANON NXT IMPLANT 68MG is approved to be sold in Singapore with effective from 2012-01-20. It is marketed by MSD PHARMA (SINGAPORE) PTE LTD, with the registration number of SIN14086P.
This product contains Etonogestrel 68mg in the form of IMPLANT. It is approved for SUBCUTANEOUS use.
This product is manufactured by N.V. ORGANONSynergy Health Ede BV. (Gamma sterilization of finished product) in NETHERLANDS.
It is a Prescription Only Medicine that can only be obtained from a doctor or a dentist, or a pharmacist with a prescription from a Singapore-registered doctor or dentist.
Description
Etonogestrel is a molecule used in hormonal contraceptives, most notably the subdermal implant Implanon.
Indication
For use as a female contraceptive (depot).
Mechanism of Action
Etonogestrel binds to the progesterone and estrogen receptors. Target cells include the female reproductive tract, the mammary gland, the hypothalamus, and the pituitary. Once bound to the receptor, progestins like etonogestrel will slow the frequency of release of gonadotropin releasing hormone (GnRH) from the hypothalamus and blunt the pre-ovulatory LH (luteinizing hormone) surge.
Toxicity
Symptoms of overdose include nausea, vomiting, vaginal bleeding, and other menstrual irregularities.
Active Ingredient/Synonyms
3-Ketodesogestrel | 3-Oxodesogestrel | Etonogestrel | étonogestrel | Etonogestrelum | Etonogestrel |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.