Product Information
Registration Status: ActiveMENOPUR MULTIDOSE POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 1200IU is approved to be sold in Singapore with effective from 2013-06-17. It is marketed by FERRING PHARMACEUTICALS PTE LTD, with the registration number of SIN14371P.
This product contains Menotrophin 1200 IU in the form of INJECTION, POWDER, FOR SOLUTION. It is approved for SUBCUTANEOUS, INTRAMUSCULAR use.
This product is manufactured by Ferring GmbH (Powder & Solvent) in GERMANY.
It is a Prescription Only Medicine that can only be obtained from a doctor or a dentist, or a pharmacist with a prescription from a Singapore-registered doctor or dentist.
Description
Menotropins contains follicle stimulating hormone (FSH) and luteinizing hormone (LH) purified from the urine of postmenopausal women. It is used as a fertility medication that is injected either subcutaneously or intramuscularly. It is composed of LH with 2 subunits, alpha = 92 residues, beta = 121 residues and FSH with 2 subunits, alpha = 92 residues, beta=111 residues.
Indication
For the treatment of female infertility
Mechanism of Action
Being a combination drug, Menotropins bind to the follicle stimulating hormone receptor (FSH), which results in ovulation in the absence of sufficient endogenous luteinizing hormone (LH). It also binds the LH receptor, thereby stimulating proper hormone release. The drug contains both FSH and LH, therefore, it induces ovarian follicular growth and development as well as gonadal steroid production in women who do not have ovarian failure. FSH is the primary driver of follicular recruitment and growth in early folliculogenesis, while LH is important for ovarian steroidogenesis and is involved in the physiological events leading to development of a competent pre-ovulatory follicle.
Active Ingredient/Synonyms
Human menopausal gonadotrophin | Menotrophin | Menotropin | Menotropins (FSH;LH) | Menotropins |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.