Product Information
Registration Status: ActiveSIN04191P
MINIMS CYCLOPENTOLATE HYDROCHLORIDE EYE DROPS 0.5% W/V is approved to be sold in Singapore with effective from 1990-04-14. It is marketed by BAUSCH & LOMB (SINGAPORE) PTE LTD, with the registration number of SIN04191P.
This product contains Cyclopentolate 0.5% w/v in the form of SOLUTION. It is approved for OPHTHALMIC use.
This product is manufactured by LABORATOIRE CHAUVIN SA in FRANCE.
It is a Prescription Only Medicine that can only be obtained from a doctor or a dentist, or a pharmacist with a prescription from a Singapore-registered doctor or dentist.
Product Reference
Important Note: For generic product, the SPC/PIL provided may not be brand specific.
{{/items}} {{^items}}Description
A parasympatholytic anticholinergic used solely to obtain mydriasis or cycloplegia. [PubChem]
Indication
Used mainly to produce mydriasis and cycloplegia for diagnostic purposes.
Mechanism of Action
By blocking muscarinic receptors, cyclopentolate produces dilatation of the pupil (mydriasis) and prevents the eye from accommodating for near vision (cycloplegia).
Pharmacokinetics
- Absorption
- Absorbed following ophthalmic administration.
- Distribution
- Metabolism
- Elimination
Toxicity
Oral LD50 in the rat is 4000 mg/kg and 960 mg/kg in the mouse. Symptoms of overdose include tachycardia, dizziness, dry mouth, behavioral disturbances, uncoordination and drowsiness.
Active Ingredient/Synonyms
(+-)-Cyclopentolate | (±)-cyclopentolate | 1-Hydroxy-alpha-phenylcyclopentaneacetic acid 2-(dimethylamino)ethyl ester | 2-(dimethylamino)Ethyl 1-hydroxy-alpha-phenylcyclopentaneacetate | 2-(dimethylamino)Ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate | 2-Phenyl-2-(1-hydroxycyclopentyl)ethanoic acid beta-(dimethylamino)ethyl ester | alpha-(1-Hydroxycyclopentyl)benzeneacetic acid 2-(dimethylamino)ethyl ester | beta-(dimethylamino)Ethyl (1-hydroxycyclopentyl)phenylacetate | beta-Dimethylaminoethyl (1-hydroxycyclopentyl)phenylacetate | Ciclopentolato | Cyclopentolate | Cyclopentolatum | α-(1-hydroxycyclopentyl)benzeneacetic acid 2-(dimethylamino)ethyl ester | β-dimethylaminoethyl (1-hydroxycyclopentyl)phenylacetate | Cyclopentolate |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.