Product Information
Registration Status: ActiveSIN04020P
MINIMS PILOCARPINE NITRATE EYE DROPS 2% W/V is approved to be sold in Singapore with effective from 1990-03-20. It is marketed by BAUSCH & LOMB (SINGAPORE) PTE LTD, with the registration number of SIN04020P.
This product contains Pilocarpine 2% w/v in the form of SOLUTION. It is approved for OPHTHALMIC use.
This product is manufactured by LABORATOIRE CHAUVIN SA in FRANCE.
It is a Prescription Only Medicine that can only be obtained from a doctor or a dentist, or a pharmacist with a prescription from a Singapore-registered doctor or dentist.
Product Reference
Important Note: For generic product, the SPC/PIL provided may not be brand specific.
{{/items}} {{^items}}Description
A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma. [PubChem]
Indication
For the treatment of radiation-induced dry mouth (xerostomia) and symptoms of dry mouth in patients with Sjögrens syndrome.
Mechanism of Action
Pilocarpine is a cholinergic parasympathomimetic agent. It increase secretion by the exocrine glands, and produces contraction of the iris sphincter muscle and ciliary muscle (when given topically to the eyes) by mainly stimulating muscarinic receptors.
Pharmacokinetics
- Absorption
- There was a decrease in the rate of absorption of pilocarpine from SALAGEN Tablets when taken with a high fat meal by 12 healthy male volunteers
- Distribution
- Metabolism
- Possibly occurs at the neuronal synapses and in the plasma
- Elimination
Active Ingredient/Synonyms
(3S-cis)-3-Ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-2(3H)-furanone | (3S,4R)-3-Ethyldihydro-4-((1-methyl-1H-imidazol-5-yl)methyl)-2(3H)-furanone | Pilocarpine | Pilocarpine |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.