Product InformationRegistration Status: Active
MIOSTAT INTRAOCULAR SOLUTION 0.01% is approved to be sold in Singapore with effective from 1990-02-06. It is marketed by ALCON PTE LTD, with the registration number of SIN04572P.
This product contains Carbachol 0.01% in the form of INJECTION. It is approved for INTRAOCULAR use.
This product is manufactured by ALCON LABORATORIES INC in UNITED STATES.
It is a Prescription Only Medicine that can only be obtained from a doctor or a dentist, or a pharmacist with a prescription from a Singapore-registered doctor or dentist.
A slowly hydrolyzed cholinergic agonist that acts at both muscarinic and nicotinic receptors.
Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.
Mechanism of Action
Carbachol is a parasympathomimetic that stimulates both muscarinic and nicotinic receptors. In topical ocular and intraocular administration its principal effects are miosis and increased aqueous humour outflow.
- Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.
Oral, mouse: LD50 = 15 mg/kg; Oral, rat: LD50 = 40 mg/kg.
(2-Carbamoyloxyethyl)trimethylammonium chloride | (2-Hydroxyethyl)trimethyl ammonium chloride carbamate | (2-Hydroxyethyl)trimethylammonium chloride carbamate | 2-((Aminocarbonyl)oxy)-N,N,N-trimethylethanaminium chloride | 2-((Aminocarbonyl)oxy)-N,N,N-trimethylethanaminum chloride | Carbachol | Carbachol chloride | Carbacholum | Carbacol | Choline carbamate chloride | Choline chloride, carbamate | Choline chlorine carbamate | Karbachol | Karbamoylcholin chlorid | Carbachol |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.