Product Information
Registration Status: ActiveMYDRIACYL STERILE OPHTHALMIC SOLUTION 0.5% is approved to be sold in Singapore with effective from 1990-06-25. It is marketed by ALCON PTE LTD, with the registration number of SIN04721P.
This product contains Tropicamide 0.50% in the form of SOLUTION. It is approved for OPHTHALMIC use.
This product is manufactured by ALCON-COUVREUR NV in BELGIUM.
It is a Prescription Only Medicine that can only be obtained from a doctor or a dentist, or a pharmacist with a prescription from a Singapore-registered doctor or dentist.
Description
One of the muscarinic antagonists with pharmacologic action similar to atropine and used mainly as an ophthalmic parasympatholytic or mydriatic. [PubChem]
Indication
Indicated to induce mydriasis (dilation of the pupil) and cycloplegia (paralysis of the ciliary muscle of the eye) in diagnostic procedures, such as measurement of refractive errors and examination of the fundus of the eye.
Mechanism of Action
Tropicamide binds to and blocks the receptors in the muscles of the eye (muscarinic receptor M4). Tropicamide acts by blocking the responses of the iris sphincter muscle to the iris and ciliary muscles to cholinergic stimulation, producing dilation of the pupil and paralysis of the ciliary muscle.
Toxicity
Overdose can casue dry mouth, blurred vision, photophobia, hallucinations and rapid/irregular pulse.
Active Ingredient/Synonyms
Tropicamid | Tropicamida | Tropicamide | Tropicamidum | Tropicamide |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.