Product Information
Registration Status: ActiveNYSTATIN VAGINAL TABLET 100,000 UNITS is approved to be sold in Singapore with effective from 1991-12-27. It is marketed by YUNG SHIN PHARMACEUTICAL (SINGAPORE) PTE LTD, with the registration number of SIN06750P.
This product contains Nystatin 100000 units in the form of TABLET. It is approved for VAGINAL use.
This product is manufactured by YUNG SHIN PHARMACEUTICAL IND CO LTD in TAIWAN.
It is a Prescription Only Medicine that can only be obtained from a doctor or a dentist, or a pharmacist with a prescription from a Singapore-registered doctor or dentist.
Description
Nystatin is a polyene antifungal drug to which many molds and yeasts are sensitive, including Candida spp. Nystatin has some toxicity associated with it when given intravenously, but it is not absorbed across intact skin or mucous membranes. It is considered a relatively safe drug for treating oral or gastrointestinal fungal infections.
Indication
For treatment of cutaneous or mucocutaneous mycotic infections caused by Candida species
Mechanism of Action
Nystatin exerts its antifungal activity by binding to ergosterol found in fungal cell membranes. Binding to ergosterol causes the formation of pores in the membrane. Potassium and other cellular constituents leak from the pores causing cell death.
Pharmacokinetics
- Absorption
- Nystatin is not absorbed from intact skin or mucous membrane.
- Distribution
- Metabolism
- Elimination
Active Ingredient/Synonyms
Nistatina | NYS | Nystatin | Nystatine | Nystatinum | Nystatin |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.