Product Information
Registration Status: ActivePICOPREP POWDER FOR ORAL SOLUTION is approved to be sold in Singapore with effective from 2013-01-30. It is marketed by FERRING PHARMACEUTICALS PTE LTD, with the registration number of SIN14303P.
This product contains Citric Acid 12g,Magnesium Oxide 3.5g, and Sodium Picosulfate 10mg in the form of POWDER, FOR SOLUTION. It is approved for ORAL use.
This product is manufactured by Ferring Pharmaceuticals (China) Co. in CHINA.
It is a Prescription Only Medicine that can only be obtained from a doctor or a dentist, or a pharmacist with a prescription from a Singapore-registered doctor or dentist.
Description
A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium chelating ability.
Toxicity
ORAL (LD50): Acute: 5040 mg/kg [Mouse]. 3000 mg/kg [Rat].
Active Ingredient/Synonyms
2-Hydroxytricarballylic acid | 3-Carboxy-3-hydroxypentane-1,5-dioic acid | Citric Acid, Anhydrous | Citronensäure | Citric Acid |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.
Description
Magnesium oxide is an inorganic compound that occurs in nature as the mineral periclase. In aqueous media combines quickly with water to form magnesium hydroxide. It is used as an antacid and mild laxative and has many nonmedicinal uses. [PubChem]
Indication
Magnesium hydroxide is used as a laxative to relieve occasional constipation (irregularity) and as an antacid to relieve indigestion, sour stomach, and heartburn.
Mechanism of Action
The term "Milk of Magnesia" was first used to describe a white aqueous, mildly alkaline suspension of magnesium hydroxide formulated at about 8%w/v. Milk of magnesia is primarily used to alleviate constipation, but can also be used to relieve indigestion and heartburn. When taken internally by mouth as a laxative, the osmotic force of the magnesia suspension acts to draw fluids from the body and to retain those already within the lumen of the intestine, serving to distend the bowel, thus stimulating nerves within the colon wall, inducing peristalsis and resulting in evacuation of colonic contents. Magnesium supplements have also been shown to reduce platelet aggregation by inhibiting in the influx of calcium, a crucial component of platelet aggregation.
Active Ingredient/Synonyms
Magmitt | Magnesium oxide |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.