Product Information
Registration Status: ActivePRIMAX EYE DROPS 5mg/ML is approved to be sold in Singapore with effective from 2006-01-17. It is marketed by PETER CHIA MARKETING PTE LTD, with the registration number of SIN13168P.
This product contains Proparacaine 5mg/ml in the form of SOLUTION, STERILE. It is approved for OPHTHALMIC use.
This product is manufactured by Ashford Laboratories Ltd in MACAU.
It is a Prescription Only Medicine that can only be obtained from a doctor or a dentist, or a pharmacist with a prescription from a Singapore-registered doctor or dentist.
Description
Proparacaine is a topical anesthetic drug of the amino ester group. It is available as its hydrochloride salt in ophthalmic solutions at a concentration of 0.5%.
Indication
Used as a local (ophthalmic) anesthetic.
Mechanism of Action
The exact mechanism whereby proparacaine and other local anesthetics influence the permeability of the cell membrane is unknown; however, several studies indicate that local anesthetics may limit sodium ion permeability through the lipid layer of the nerve cell membrane. Proparacaine may alter epithelial sodium channels through interaction with channel protein residues. This limitation prevents the fundamental change necessary for the generation of the action potential.
Active Ingredient/Synonyms
Proximetacaina | Proxymetacaine | Proxymetacainum | Proparacaine |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.