Product InformationRegistration Status: Active
PROPANOL TABLET 40mg is approved to be sold in Singapore with effective from 1988-02-06. It is marketed by BEACONS PHARMACEUTICALS PTE LTD, with the registration number of SIN01621P.
This product contains Propranolol 40mg in the form of TABLET, FILM-COATED. It is approved for ORAL use.
This product is manufactured by BEACONS PHARMACEUTICALS PTE LTD in SINGAPORE.
It is a Prescription Only Medicine that can only be obtained from a doctor or a dentist, or a pharmacist with a prescription from a Singapore-registered doctor or dentist.
A widely used non-cardioselective beta-adrenergic antagonist. Propranolol is used in the treatment or prevention of many disorders including acute myocardial infarction, arrhythmias, angina pectoris, hypertension, hypertensive emergencies, hyperthyroidism, migraine, pheochromocytoma, menopause, and anxiety. [PubChem]
For the prophylaxis of migraine.
Mechanism of Action
Propranolol competes with sympathomimetic neurotransmitters such as catecholamines for binding at beta(1)-adrenergic receptors in the heart, inhibiting sympathetic stimulation. This results in a reduction in resting heart rate, cardiac output, systolic and diastolic blood pressure, and reflex orthostatic hypotension.
- Propranolol is almost completely absorbed from the GI tract; however, plasma concentrations attained are quite variable among individuals.
- * 4 L
Symptoms of overdose include bradycardia, cardiac failure, hypotension, and brochospasm. LD50=565 mg/kg (orally in mice).
1-((1-Methylethyl)amino)-3-(1-naphthalenyloxy)-2-propanol | 1-(isopropylamino)-3-(1-naphthyloxy)propan-2-ol | beta-Propranolol | Propanalol | Propanolol | Propranolol | Propranololo | Propranololum | β-Propranolol | Propranolol |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.