Product InformationRegistration Status: Active
SOFICLOR FOR ORAL SUSPENSION 125mg/5ml is approved to be sold in Singapore with effective from 2001-11-27. It is marketed by APEX PHARMA MARKETING PTE LTD, with the registration number of SIN11733P.
This product contains Cefaclor 125mg/5ml in the form of GRANULE, FOR SUSPENSION. It is approved for ORAL use.
This product is manufactured by XEPA-SOUL PATTINSON (MALAYSIA) SDN BHD in MALAYSIA.
It is a Prescription Only Medicine that can only be obtained from a doctor or a dentist, or a pharmacist with a prescription from a Singapore-registered doctor or dentist.
Semisynthetic, broad-spectrum antibiotic derivative of cephalexin.
For the treatment of certain infections caused by bacteria such as pneumonia and ear, lung, skin, throat, and urinary tract infections.
Mechanism of Action
Cefaclor, like the penicillins, is a beta-lactam antibiotic. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins. It is possible that cefaclor interferes with an autolysin inhibitor.
- Well absorbed after oral administration, independent of food intake.
- No appreciable biotransformation in liver (approximately 60% to 85% of the drug is excreted unchanged in the urine within 8 hours).
Symptoms of overdose include diarrhea, nausea, stomach upset, and vomiting.
3-Chloro-7-D-(2-phenylglycinamido)-3-cephem-4-carboxylic acid | CCL | Cefaclor | Cefaclor anhydrous | Cefacloro | Cefaclorum | Céfeaclor | Cephaclor | Cefaclor |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.