Product Information
Registration Status: ActiveSTANDACILLIN FOR INJECTION 0.5g/VIAL is approved to be sold in Singapore with effective from 1988-03-05. It is marketed by NOVARTIS (SINGAPORE) PTE LTD, with the registration number of SIN00680P.
This product contains Ampicillin 500mg/vial in the form of INJECTION, POWDER, FOR SOLUTION. It is approved for INTRAVENOUS, INTRAMUSCULAR use.
This product is manufactured by SANDOZ GMBH in AUSTRIA.
It is a Prescription Only Medicine that can only be obtained from a doctor or a dentist, or a pharmacist with a prescription from a Singapore-registered doctor or dentist.
Description
Ampicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
Indication
For treatment of infection (Respiratory, GI, UTI and meningitis) due to E. coli, P. mirabilis, enterococci, Shigella, S. typhosa and other Salmonella, nonpenicillinase-producing N. gononhoeae, H. influenzae, staphylococci, streptococci including streptoc
Mechanism of Action
By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, Ampicillin inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that Ampicillin interferes with an autolysin inhibitor.
Active Ingredient/Synonyms
(2S,6R)-6-{[(2R)-2-amino-2-phenylethanoyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid | 6-(D-(2-amino-2-phenylacetamido))-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid | ABPC | Aminobenzylpenicillin | Ampicilina | Ampicillin | Ampicillin (anhydrous) | Ampicillin Acid | Ampicillin Anhydrous | Ampicillin, anhydrous | Ampicilline | Ampicillinum | Anhydrous ampicillin | AP | D-(−)-6-(α-aminophenylacetamido)penicillanic acid | D-(−)-ampicillin | Ampicillin |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.