Product Information

Registration Status: Active

UROKINASE-GREEN CROSS INJ. 60,000 IU/VIAL is approved to be sold in Singapore with effective from 1999-05-10. It is marketed by GRIFOLS ASIA PACIFIC PTE LTD, with the registration number of SIN11140P.

This product contains Urokinase 60000 iu/vial in the form of INJECTION, POWDER, FOR SOLUTION. It is approved for INTRAVENOUS use.

This product is manufactured by CHINA CHEMICAL & PHARMACEUTICAL CO. in TAIWAN.

It is a Prescription Only Medicine that can only be obtained from a doctor or a dentist, or a pharmacist with a prescription from a Singapore-registered doctor or dentist.



Low molecular weight form of human urokinase, that consists of an A chain of 2,000 daltons linked by a sulfhydryl bond to a B chain of 30,400 daltons. Recombinant urokinase plasminogen activator


Urokinase can be used for the treatment of pulminary embolism, coronary artery thrombosis, IV catheter clearance, and venous and arterial blood clots.

Mechanism of Action

Urokinase acts on the endogenous fibrinolytic system. It cleaves the Arg-Val bond in plasminogen to produce active plasmin. Plasmin degrades fibrin clots as well as fibrinogen and other plasma proteins.

Active Ingredient/Synonyms

U-plasminogen activator | uPA | Urokinase-type plasminogen activator precursor | Urokinase |

Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.


  1. Health Science Authority of Singapore - Reclassified POM
  2. Drugbank