X

VERPAMIL INJECTION 2.5mg/ML

Product Information

Registration Status: Active

SIN00937P

VERPAMIL INJECTION 2.5mg/ML is approved to be sold in Singapore with effective from 1988-09-05. It is marketed by PHARMACON PTE LTD, with the registration number of SIN00937P.

This product contains Verapamil 2.5mg/ml in the form of INJECTION. It is approved for INTRAVENOUS use.

This product is manufactured by ORION CORPORATION (ESPOO PLANT) in FINLAND.

It is a Prescription Only Medicine that can only be obtained from a doctor or a dentist, or a pharmacist with a prescription from a Singapore-registered doctor or dentist.

Product Reference
Loading...


Description

A calcium channel blocker that is a class IV anti-arrhythmia agent.

Indication

For the treatment of hypertension, angina, and cluster headache prophylaxis.

Mechanism of Action

Verapamil inhibits voltage-dependent calcium channels. Specifically, its effect on L-type calcium channels in the heart causes a reduction in ionotropy and chronotropy, thuis reducing heart rate and blood pressure. Verapamil's mechanism of effect in cluster headache is thought to be linked to its calcium-channel blocker effect, but which channel subtypes are involved is presently not known.

Pharmacokinetics

Absorption
90%
Distribution
Metabolism
Elimination

Toxicity

LD50=8 mg/kg (i.v. in mice)

Active Ingredient/Synonyms

Iproveratril | Vérapamil | Verapamil | Verapamilo | Verapamilum | Verapamil |


Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.

References

  1. Health Science Authority of Singapore - Reclassified POM
  2. Drugbank

Pharmfair.com uses cookies to improve your browsing experience. We'll assume you're ok with this, but you can opt-out if you wish. Peace!