Product Information
Registration Status: ActiveSIN15527P
ALERCHEK OPHTHALMIC SOLUTION 0.1% is approved to be sold in Singapore with effective from 2018-08-17. It is marketed by DCH AURIGA SINGAPORE, with the registration number of SIN15527P.
This product contains Olopatadine 1.00mg/ml in the form of SOLUTION, STERILE. It is approved for OPHTHALMIC use.
This product is manufactured by Indoco Remedies Limited in INDIA.
It is a has been granted the exemption for supply without a presciption if it met certain criteria.
Product Reference
Important Note: For generic product, the SPC/PIL provided may not be brand specific.
{{/items}} {{^items}}Description
Used to treat allergic conjunctivitis (itching eyes), olopatadine inhibits the release of histamine from mast cells. It is a relatively selective histamine H1 antagonist that inhibits the in vivo and in vitro type 1 immediate hypersensitivity reaction including inhibition of histamine induced effects on human conjunctival epithelial cells.
Indication
For the treatment of ocular itching associated with allergic conjunctivitis.
Mechanism of Action
Olopatadine is a selective histamine H1 antagonist that binds to the histamine H1 receptor. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms brought on by histamine. Olopatadine is devoid of effects on alpha-adrenergic, dopamine and muscarinic type 1 and 2 receptors.
Pharmacokinetics
- Absorption
- Ophthalmic use of olopatadine usually does not produce measurable plasma concentrations.
- Distribution
- Metabolism
- The mono-desmethyl and the N-oxide metabolites have been detected at low concentrations in the urine.
- Elimination
Active Ingredient/Synonyms
Olopatadin | Olopatadina | Olopatadine | Olopatadinum | Opatanol | Olopatadine |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.