Source of information: Drugbank (External Link). Last updated on: 3rd July 18
*Trade Name used in the content below may not be the same as the HSA-registered product.
Active Ingredient / Synonyms
1-Butanoic acid-2-(O-methyl-L-tyrosine)-1-carbaoxytocin | 1-Butyric acid-2-(3-(P-methoxyphenyl)-L-alanine)oxytocin | Carbetocino | Carbetocinum | Deamino-2-O-methyltyrosine-1-carbaoxytocin | Carbetocin |
Carbetocin is a drug used to control postpartum hemorrhage, bleeding after giving birth. It is an analogue of oxytocin, and its action is similar to that of oxytocin -- it causes contraction of the uterus.
Used to control postpartum hemorrhage and bleeding after giving birth.
Mechanism of Action
Carbetocin binds to oxytocin receptors present on the smooth musculature of the uterus, resulting in rhythmic contractions of the uterus, increased frequency of existing contractions, and increased uterine tone. The oxytocin receptor content of the uterus is very low in the non-pregnant state, and increases during pregnancy, reaching a peak at the time of delivery.
Carbetocin is a drug used to control postpartum hemorrhage, bleeding after giving birth. It is sold under the trade name Duratocin. It is an analogue of oxytocin, and its action is similar to that of oxytocin; it causes contraction of the uterus.
Bioavailability is 80% following intramuscular injection.
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