HSA Reclassified Drug | Exemptions For Supply of Beclomethasone Without Prescription



Eligible Active Ingredient: Beclomethasone. As nasal spray
With Effective From: 17-Jan-2000
Indication Permitted: Prevention and treatment of allergic rhinitis.
Maximum Daily Dose: 200 mcg/nostril
Maximum Supply per Transaction: Up to 3 months’ duration.
Minimum Age of User: 18 years
Patient Information Leaflet from HSA/PSS: Download PIL (Link to HSA website)


Mechanism of Action of Beclomethasone

Unbound corticosteroids cross cell membranes and bind with high affinity to specific cytoplasmic receptors. The result includes inhibition of leukocyte infiltration at the site of inflammation, interference in the function of mediators of inflammatory response, suppression of humoral immune responses, and reduction in edema or scar tissue. The antiinflammatory actions of corticosteroids are thought to involve phospholipase A2 inhibitory proteins, lipocortins, which control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes. For the investigated use in the treatment of GvHD or Crohn’s, beclometasone acts by binding to interleukin-13 to inhibit cytokines, which in turn inhibits inflammatory chemicals downstream.

Additional Information of Beclomethasone

Pharmacology Class: Decongestants And Other Nasal Preparations For Topical Use
Therapeutic Class: Nasal Preparations
Chemical Class: Corticosteroids
Synonyms: (11β,16β)-9-chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione | 9-chloro-11β-hydroxy-16β-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate | 9-chloro-16β-methyl-11β,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-dipropionate | beclometasone 17,21-dipropionate | Beclometasone dipropionate

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HSA-registered therapeutic products granted exemption to supply without prescription


  1. Health Science Authority of Singapore – Reclassified POM
  2. Drugbank

HSA-Registered Products Containing Beclomethasone As nasal spray

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This list is not exhaustive. HSA collaborates with Pharmaceurical Society of Singapore (PSS) to review the appropriate use of therapeutic products in the community from time to time. Hence, HSA may enable the supply of a Prescription Only Medicine (POM) by pharmacists without a prescription, upon review that the product can be used in a safe and effective manner under the supervision of a pharmacist. This can be effected through legislative mechanisms in the absence of an application made by the product registrant to reclassify the therapeutic product, subject to to conditions including indication, strength, maximum daily dose, maximum supply quantity, and age restriction.