HSA Reclassified Drug | Exemptions For Supply of Fexofenadine Syrup Without Prescription


Eligible Active Ingredient: Fexofenadine Syrup. As an oral liquid preparation not exceeding 6mg/ml
With Effective From: 1-Jun-17
Indication Permitted: Indications: For the symptomatic treatment of allergic rhinitis and chronic idiopathic urticarial
Maximum Daily Dose: 60mg
Maximum Supply per Transaction: 150ml
Minimum Age of User: 2 years
Patient Information Leaflet from HSA/PSS: Download PIL (Link to HSA website)

Mechanism of Action of Fexofenadine Syrup

Like other H1-blockers, Fexofenadine competes with free histamine for binding at H1-receptors in the GI tract, large blood vessels, and bronchial smooth muscle. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms (eg. nasal congestion, watery eyes) brought on by histamine. Fexofenadine exhibits no anticholinergic, antidopaminergic, alpha1-adrenergic or beta-adrenergic-receptor blocking effects.

Additional Information of Fexofenadine Syrup

Pharmacology Class: Antihistamines For Systemic Use
Therapeutic Class: Antihistamines For Systemic Use
Chemical Class: Other Antihistamines For Systemic Use
Synonyms: 4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)butyl)-alpha,alpha-dimethylbenzeneacetic acid | Carboxyterfenadine | Fexofenadine | Terfenadine acid metabolite | Terfenadine carboxylate | Terfenadine-COOH

Show All HSA-registered therapeutic products granted exemption to supply without prescription


  1. Health Science Authority of Singapore – Reclassified POM
  2. Drugbank

HSA-Registered Products Containing Fexofenadine Syrup As an oral liquid preparation not exceeding 6mg/ml

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This list is not exhaustive. HSA collaborates with Pharmaceurical Society of Singapore (PSS) to review the appropriate use of therapeutic products in the community from time to time. Hence, HSA may enable the supply of a Prescription Only Medicine (POM) by pharmacists without a prescription, upon review that the product can be used in a safe and effective manner under the supervision of a pharmacist. This can be effected through legislative mechanisms in the absence of an application made by the product registrant to reclassify the therapeutic product, subject to to conditions including indication, strength, maximum daily dose, maximum supply quantity, and age restriction.