HSA Reclassified Drug | Exemptions For Supply of Nystatin Without Prescription


Eligible Active Ingredient: Nystatin. As an oral liquid preparation containing not more than 100,000 units per ml
With Effective From: 1-Apr-15
Indication Permitted: Treatment of Oral Candidiasis
Maximum Daily Dose: Infants and children 6 months and older: 400,000 units
Adults: 2.4 million units
Maximum Supply per Transaction: 2 weeks
Minimum Age of User: 6 months
Patient Information Leaflet from HSA/PSS: Download PIL (Link to HSA website)

Mechanism of Action of Nystatin

Nystatin exerts its antifungal activity by binding to ergosterol found in fungal cell membranes. Binding to ergosterol causes the formation of pores in the membrane. Potassium and other cellular constituents leak from the pores causing cell death.

Additional Information of Nystatin

Pharmacology Class: Intestinal Antiinfectives
Therapeutic Class: Antidiarrheals, Intestinal Antiinflammatory/Antiinfective Agents
Chemical Class: Antibiotics
Synonyms: Nistatina | NYS | Nystatin | Nystatine | Nystatinum

Show All HSA-registered therapeutic products granted exemption to supply without prescription


  1. Health Science Authority of Singapore – Reclassified POM
  2. Drugbank

HSA-Registered Products Containing Nystatin As an oral liquid preparation containing not more than 100,000 units per ml

wpDataTable with provided ID not found!

This list is not exhaustive. HSA collaborates with Pharmaceurical Society of Singapore (PSS) to review the appropriate use of therapeutic products in the community from time to time. Hence, HSA may enable the supply of a Prescription Only Medicine (POM) by pharmacists without a prescription, upon review that the product can be used in a safe and effective manner under the supervision of a pharmacist. This can be effected through legislative mechanisms in the absence of an application made by the product registrant to reclassify the therapeutic product, subject to to conditions including indication, strength, maximum daily dose, maximum supply quantity, and age restriction.