Product Information
Registration Status: ActiveSIN00288P
APO-TRIFLUOPERAZINE TABLET 1mg is approved to be sold in Singapore with effective from 1988-04-21. It is marketed by PHARMAFORTE SINGAPORE PTE LTD, with the registration number of SIN00288P.
This product contains Trifluoperazine 1mg in the form of TABLET, FILM-COATED. It is approved for ORAL use.
This product is manufactured by APOTEX INC in CANADA.
It is a Prescription Only Medicine that can only be obtained from a doctor or a dentist, or a pharmacist with a prescription from a Singapore-registered doctor or dentist.
Product Reference
Important Note: For generic product, the SPC/PIL provided may not be brand specific.
{{/items}} {{^items}}Description
A phenothiazine with actions similar to chlorpromazine. It is used as an antipsychotic and an antiemetic. [PubChem]
Indication
For the treatment of anxiety disorders, depressive symptoms secondary to anxiety and agitation.
Mechanism of Action
Trifluoperazine blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain; depresses the release of hypothalamic and hypophyseal hormones and is believed to depress the reticular activating system thus affecting basal metabolism, body temperature, wakefulness, vasomotor tone, and emesis.
Toxicity
Symptoms of overdose include agitation, coma, convulsions, difficulty breathing, difficulty swallowing, dry mouth, extreme sleepiness, fever, intestinal blockage, irregular heart rate, low blood pressure, and restlessness.
Active Ingredient/Synonyms
10-[3-(4-Methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-10H-phenothiazine | 10-[3-(4-METHYL-piperazin-1-yl)-propyl]-2-trifluoromethyl-10H-phenothiazine | Trifluoperazina | Trifluoperazine | Trifluoperazinum | Trifluoromethyl-10-(3'-(1-methyl-4-piperazinyl)propyl)phenothiazine | Trifluoroperazine | Trifluperazine | Trifluoperazine |
Source of information: Drugbank (External Link). Last updated on: 3rd July 18. *Trade Name used in the content below may not be the same as the HSA-registered product.